Herbal Side Effects | Danger Extracts St. John’s wort if taken together with Synthetic Drugs
St. john's wort (Hypericum perforatum)
Extract of St. John’s wort (Hypericum perforatum), which now often found in a wide variety of food supplements to maintain women’s health, it has a negative effect if consumed along with several types of synthetic drugs. The use of extracts St. John’s wort along with synthetic drugs such as inhibitors serotinin accelerator like trazodona, sertralina, and nefazodona, it can cause serotonin syndrome was. These plant extracts can also increasing concentration of teofilina inside the body if used simultaneously.
Conversely, if the extract of St. John’s wort used in conjunction with cyclosporin, it will reduce the concentration of cyclosporin in the serum causing these antibiotics ineffective.
The use of extracts St. John’s wort along with drugs such as oral contraceptives etinilestradiol or desogestrol, can cause bleeding.
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